| ABSTRACT Endocrine disruptors are exogenous substances that can impair one or more functions of the endocrine system and cause adverse effects to the health of an intact organism. The main goal of this study was to evaluate the effect of the endocrine disruptors 17β-estradiol (E2) and 17α-ethinyl estradiol (EE2) on the sexual differentiation of Nile tilapia during spawning. Six treatments and one control with three replications, totalizing 21 experimental units, were assessed in a completely randomized design. Hormones were dosed at concentrations of 250, 500, and 1,000 ng L−1 (treatments E2-250, E2-500, E2-1,000, EE2-250, EE2-500, and EE2-1,000). Exposure to hormones occurred during the first 28 days of life. After this period, water was completely... |
